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Breviscapine remodels myocardial glucose and lipid metabolism by regulating serotonin to alleviate doxorubicin-induced cardiotoxicity

The broad-spectrum anticancer drug doxorubicin (Dox) is associated with a high incidence of cardiotoxicity, which severely affects the clinical application of the drug and patients’ quality of life. Here, we assess how Dox modulates myocardial energy and contractile function and this could aid the development of relevant protective drugs.

Breviscapine remodels myocardial glucose and lipid metabolism by regulating serotonin to alleviate doxorubicin-induced cardiotoxicity Read More »

Polygonum capitatum, the Hmong Medicinal Flora: A Comprehensive Review of Its Phytochemical, Pharmacological and Pharmacokinetic Characteristics

Polygonum capitatum, known as “Tou Hua Liao” (Chinese name), is a crucial source of Hmong medicinal plants that has benefited human health for a long time. This folk-medicinal plant is widely distributed in the south-west of China for the treatment of various urologic disorders including urinary tract infections, pyelonephritis, and urinary calculus.

Polygonum capitatum, the Hmong Medicinal Flora: A Comprehensive Review of Its Phytochemical, Pharmacological and Pharmacokinetic Characteristics Read More »

17 Medicinal Health Benefits Of Flowery Knotweed (Polygonum capitatum)

Flowery Knotweed, scientifically known as Polygonum capitatum, is a herbaceous perennial plant belonging to the Polygonaceae family. Native to East Asia, particularly China, Japan, and Korea, it has become naturalized in various regions around the world. Commonly referred to as “knotweed,” this plant is recognized for its vigorous growth, distinctive knot-like clusters of flowers, and invasive nature.

17 Medicinal Health Benefits Of Flowery Knotweed (Polygonum capitatum) Read More »

Breviscapine: A Review on its Phytochemistry, Pharmacokinetics and Therapeutic Effects

Breviscapine is one of the extracts of several flavonoids of Erigeron breviscapus. Scutellarin is the main active component of breviscapine, and the qualitative or quantitative criteria as well. Scutellarin and its analogs share a similar skeleton of the flavonoids. Breviscapine has been widely used in the treatment of cerebral infarction and its sequelae, cerebral thrombus, coronary heart disease (CHD), and angina pectoris.

Breviscapine: A Review on its Phytochemistry, Pharmacokinetics and Therapeutic Effects Read More »

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