Modern Methods of Preparation
Developed a nanoemulsions (NE) drug delivery system for breviscapine, a cardiovascular drug extracted from E. breviscapus. All the studies implicated that the NE carrier contributed to the enhancement of the oral absorption due to the improved stability and permeation in the gastrointestinal tract. Ma 2015
Developed solid dispersion tablets consisting of breviscapine, polyvinylpyrrolidone K30, microcrystalline cellulose and crospovidone. Results showed substantial increase in dissolution rate and bioavailability vs. standard tablets. Breviscapine is a cardiovascular drug extracted from E. breviscapus. Cong 2014
A review of evidence on novel modern methods of preparations of breviscapine-based drugs, with a focus on water solubility and bioavailability. Breviscapine, a flavone glucuronide, is a cardiovascular medicine extracted from a Chinese herb Erigeron breviscapinus. [Article in Chinese] Tian 2014
Developed a nanostructured lipid carrier as a novel sustained release system for breviscapine with improved pharmokinetic profile. Brevisacapine is one of the cardiovascular drugs extracted from a Chinese herb Erigeron breviscapinus. Li 2013
Optimized the preparation process of Erigeron breviscapus sustained-release pellets through combining back-propagation artificial neural network modeling with particle swarm optimization algorithm. [Article in Chinese] Zhang 2012
Optimized a method of preparing breviscapine dispersible tablets by orthogonal experiment design. Breviscapine is one of the cardiovascular drugs extracted from a Chinese herb Erigeron breviscapinus. [Article in Chinese] Ding 2010
Synthesis and physiochemical characterization of an esterified prodrug of scutellarin from Erigeron breviscapus, with the goal of improving absorption. [Article in Chinese] Cao 2006